Substrate: Alpha-actinin 1 (F-actin cross linking protein)
Seq-ID: P12814 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-45875   KCC2A_HUMAN
MINT-45879   KCC2A_RAT
MINT-72665   HS90B_HUMAN
MINT-2856533   ATX2_HUMAN
MINT-2856571   COIL_HUMAN
MINT-6795322   SRC_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
calcium ion binding,
vinculin binding,
actin binding,
integrin binding		 focal adhesion,
pseudopodium,
cytosol,
nucleolus,
actin cytoskeleton,
Z disc		 regulation of apoptosis,
negative regulation of cellular component movement,
focal adhesion assembly
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 12 DHYDSQQTNDYMQPEEDWDRD FAK 11369769
LTP
0.78
 - -
0.55
 --
T 50 WCNSHLRKAGTQIENIEEDFR - 16097034
HTP
0.93
 - CH
0.34
 2EYI 21.23%
S 140 IILRFAIQDISVEETSAKEGL - 18669648
HTP
0.87
 - -
0.07
 2EYI 69.67%
Y 193 IHRHRPELIDYGKLRKDDPLT - 18083107
HTP
0.94
 - CH
0.29
 2EYI 11.35%

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